Thomas J. Hardcastle


About Me:

I am a post-doctoral researcher working in the Genetics and Epigenetics group of Prof. Sir David Baulcombe's group at the Department of Plant Sciences of the University of Cambridge. I completed my PhD thesis, 'Model-Driven Analysis of High-Throughput Genomic Data in Late Stage Ovarian Cancer', with Prof. Simon Tavare and Dr. James Brenton at the Department of Oncology at the University of Cambridge.

Research:

My research focuses on the development and application of computational tools in bioinformatics and especially tools for analysis of data from next-generation sequencing machines. At present, this work is motivated by the analysis of small RNA data, particularly with a view to identification of siRNA precursors and the analysis of patterns of differential expression between diverse sample groups.

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